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This is SGEM

SGEM stands for Stockholm Genetically Engineered Machines and is a non-profit association, founded in 2015 to ensure annual participation in the iGEM competition by a team from Stockholm. Learn more


iGEM Stockholm 2019

Esther: the new tool for improved phage therapy

Phage therapy has gained much attention over the last years, utilizing the natural capability of bacteriophages to eradicate harmful pathogens. Nonetheless, it is still far from being available to the general public; mostly due an inconsistent delivery efficiency. Our aim is to provide a new method to deliver temperate phages – this is, phages that have both a lysogenic and a lytic cycle. Harmless bacteria are used as vehicle for phages, which will remain integrated in the bacterial DNA through the lysogenic cycle. Using our genetically modified switch, the lytic cycle is triggered once the vehicle has reached the site of infection, releasing a high dose of localized bacteriophages, ready to infect pathogenic bacteria. Named after the famous microbiologist that discovered the lambda phage, Esther Ledeberg, and as a tribute to all women in science, we have named this new tool for improved phage therapy Esther.

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Previous teams

iGEM Stockholm 2015

ABBBA : Affinity-Based Bacterial Biomarker Assay

Awarded
Gold Medal
Nomination for Best Health and Medicine Project

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iGEM Stockholm 2016

SMITE : Spider silk Mediated Infection Treatment

Awarded
Gold Medal
Nomination for Best Education & Public Engagement
Nomination for Best Presentation Read more

iGEM Stockholm 2017

PROlung a mucus degrading lung probiotic

Awarded
Gold Medal
Nomination for Best Entrepreneurship

Read more

iGEM Stockholm 2018

ABiotic Blue: Fighting antibiotic pollutants in the Baltic Sea

Awarded

Gold medal
Winner of Best Environment Project
Winner of Best Integrated Human Practices
Nominated for Best Presentation
Nominated for Best Entrepreneurship
Nominated for Best Product Design
Nominated for Best Model
Nominated for Best Integrated Human Practices
Nominated for Best Education & Public Engagement

Read more